22. Santiago, Chile
> Air quality ranking April 8, 2022: 101, 22 worst among 95 major cities
> Avg. annual PM2.5 concentration (μg/m³) in 2021: 25.8
> Worst month in 2021: July (51.1)
> Avg. annual PM2.5 concentration in 2020: 23.6
> Total population in 2022: 6,856,939
21. Krasnoyarsk, Russia
> Air quality ranking April 8, 2022: 104, 21 worst among 95 major cities
> Avg. annual PM2.5 concentration (μg/m³) in 2021: 49.8
> Worst month in 2021: August (148.4)
> Avg. annual PM2.5 concentration in 2020: 14.7
> Total population in 2022: 1,158,761
20. Mumbai, India
> Air quality ranking April 8, 2022: 106, 20 worst among 95 major cities
> Avg. annual PM2.5 concentration (μg/m³) in 2021: 46.4
> Worst month in 2021: January (98.5)
> Avg. annual PM2.5 concentration in 2020: 41.3
> Total population in 2022: 20,961,472
19. Hangzhou, China
> Air quality ranking April 8, 2022: 108, 19 worst among 95 major cities
> Avg. annual PM2.5 concentration (μg/m³) in 2021: 27.4
> Worst month in 2021: December (45.8)
> Avg. annual PM2.5 concentration in 2020: 29.0
> Total population in 2022: 8,044,878
18. Karachi, Pakistan
> Air quality ranking April 8, 2022: 112, 18 worst among 95 major cities
> Avg. annual PM2.5 concentration (μg/m³) in 2021: 45.9
> Worst month in 2021: January (97.9)
> Avg. annual PM2.5 concentration in 2020: 43.8
> Total population in 2022: 16,839,950
